The Essence of Lupus

Lupus is a complex autoimmune disease. In people with lupus, the immune system turns against parts of the body it is designed to protect. Lupus can affect many parts of the body, including the organs.Systemic lupus erythematosus (SLE) is the form of the disease that most people are think of when they speak of lupus. Systemic implies that the disease can affect many parts of the body, including organs.

http://arthritis.about.com/od/lupus/a/guidetolupus.htm 

Lupus - 10 Things You Should Know

Lupus is a complicated disease. Whether it has been suggested you may have lupus, or you have a definitive diagnosis, you should know these 10 basic facts about lupus.
In lupus, the immune system of the body attacks its own cells and tissues. Specifically, the joints, skin, kidneys, lungs, heart, nervous system, and other organs of the body are affected.

http://arthritis.about.com/od/lupus/a/lupus_facts.htm